اثربخشی تحریک الکتریکی مستقیم فراجمجمهای مغز (tDCS) بر کارکردهای اجرایی و انعطافپذیری شناختی بیماران مبتلا به افسردگی اساسی
کلمات کلیدی:
تحریک الکتریکی فراجمجمهای, کارکردهای اجرایی, انعطافپذیری شناختی, افسردگی اساسیچکیده
هدف پژوهش حاضر بررسی اثربخشی تحریک الکتریکی مستقیم فراجمجمهای مغز بر بهبود کارکردهای اجرایی و انعطافپذیری شناختی در بیماران مبتلا به افسردگی اساسی بود. این پژوهش نیمهآزمایشی با طرح پیشآزمون ـ پسآزمون و گروه گواه بر روی ۳۰ زن ۲۰ تا ۳۵ ساله مبتلا به افسردگی اساسی در تهران انجام شد. آزمودنیها بهصورت تصادفی در دو گروه آزمایش و گواه قرار گرفتند. گروه آزمایش طی شش جلسه بیستدقیقهای، دو بار در هفته تحت مداخله tDCS قرار گرفت و گروه گواه مداخلهای دریافت نکرد. ابزارهای پژوهش شامل پرسشنامه افسردگی بک، آزمون انبک و آزمون انعطافپذیری شناختی بود. دادهها با تحلیل کوواریانس چندمتغیره و اندازهگیری مکرر تحلیل شدند. نتایج تحلیل کوواریانس چندمتغیره نشان داد مداخله tDCS بهطور معناداری موجب بهبود کارکردهای اجرایی و افزایش انعطافپذیری شناختی در گروه آزمایش نسبت به گروه گواه شد (p<0.001). تحریک الکتریکی مستقیم فراجمجمهای مغز میتواند بهعنوان یک مداخله مؤثر و ایمن در بهبود عملکردهای شناختی بیماران مبتلا به افسردگی اساسی مورد استفاده قرار گیرد.
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حق نشر 1404 معصومه ساعدکاظمی, فرزانه خسروی, زهره پورمعصومی حسن کیاده (نویسنده); سیده نفیسه محسنی منصور (نویسنده مسئول); کامران پورمحمدقوچانی , گیتی شهبازی (نویسنده)

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